About   Help   FAQ
Gene Expression Literature Summary
Assay
Age
In situ reporter (knock in)
9.5 DPC

19 matching records from 19 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Kdr  kinase insert domain protein receptor   (Synonyms: Flk1, Flk-1, orv, vascular endothelial growth factor receptor- 2, VEGFR2, VEGFR-2, VEGF receptor-2)
Results  Reference
1J:237925 Azizoglu DB, Chong DC, Villasenor A, Magenheim J, Barry DM, Lee S, Marty-Santos L, Fu S, Dor Y, Cleaver O, Vascular development in the vertebrate pancreas. Dev Biol. 2016 Dec 01;420(1):67-78
1J:233988 Barry DM, Xu K, Meadows SM, Zheng Y, Norden PR, Davis GE, Cleaver O, Cdc42 is required for cytoskeletal support of endothelial cell adhesion during blood vessel formation in mice. Development. 2015 Sep 1;142(17):3058-70
1J:174608 Chong DC, Koo Y, Xu K, Fu S, Cleaver O, Stepwise arteriovenous fate acquisition during mammalian vasculogenesis. Dev Dyn. 2011 Sep;240(9):2153-65
1J:115663 Duan LJ, Imamoto A, Fong GH, Dual roles of the C-terminal Src kinase (Csk) during developmental vascularization. Blood. 2004 Feb 15;103(4):1370-2
1J:109435 Ema M, Takahashi S, Rossant J, Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors. Blood. 2006 Jan 1;107(1):111-7
1J:296645 Hamline MY, Corcoran CM, Wamstad JA, Miletich I, Feng J, Lohr JL, Hemberger M, Sharpe PT, Gearhart MD, Bardwell VJ, OFCD syndrome and extraembryonic defects are revealed by conditional mutation of the Polycomb-group repressive complex 1.1 (PRC1.1) gene BCOR. Dev Biol. 2020 Jul 18;
1*J:287156 Ishitobi H, Matsumoto K, Azami T, Itoh F, Itoh S, Takahashi S, Ema M, Flk1-GFP BAC Tg mice: an animal model for the study of blood vessel development. Exp Anim. 2010;59(5):615-22
1*J:50309 Lin Q, Lu J, Yanagisawa H, Webb R, Lyons GE, Richardson JA, Olson EN, Requirement of the MADS-box transcription factor MEF2C for vascular development. Development. 1998 Nov;125(22):4565-74
1*J:187742 Mould A, Morgan MA, Li L, Bikoff EK, Robertson EJ, Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta. Genes Dev. 2012 Sep 15;26(18):2063-74
1J:104918 Seki T, Hong KH, Oh SP, Nonoverlapping expression patterns of ALK1 and ALK5 reveal distinct roles of each receptor in vascular development. Lab Invest. 2006 Feb;86(2):116-29
1*J:85877 Seki T, Yun J, Oh SP, Arterial endothelium-specific activin receptor-like kinase 1 expression suggests its role in arterialization and vascular remodeling. Circ Res. 2003 Oct 3;93(7):682-9
1*J:26846 Shalaby F, Rossant J, Yamaguchi TP, Gertsenstein M, Wu XF, Breitman ML, Schuh AC, Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature. 1995 Jul 6;376(6535):62-6
1*J:116891 Tanaka M, Okudaira S, Kishi Y, Ohkawa R, Iseki S, Ota M, Noji S, Yatomi Y, Aoki J, Arai H, Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid. J Biol Chem. 2006 Sep 1;281(35):25822-30
1J:204328 Tondeleir D, Drogat B, Slowicka K, Bakkali K, Bartunkova S, Goossens S, Haigh JJ, Ampe C, Beta-Actin Is Involved in Modulating Erythropoiesis during Development by Fine-Tuning Gata2 Expression Levels. PLoS One. 2013;8(6):e67855
1J:269444 Watanabe C, Matsushita J, Azami T, Tsukiyama-Fujii S, Tsukiyama T, Mizuno S, Takahashi S, Ema M, Generating Vegfr3 reporter transgenic mouse expressing membrane-tagged Venus for visualization of VEGFR3 expression in vascular and lymphatic endothelial cells. PLoS One. 2019;14(1):e0210060
1*J:64329 Welsh IC, O'Brien TP, Loss of late primitive streak mesoderm and interruption of left-right morphogenesis in the Ednrb(s-1Acrg) mutant mouse. Dev Biol. 2000 Sep 1;225(1):151-68
1J:174152 Xu K, Sacharidou A, Fu S, Chong DC, Skaug B, Chen ZJ, Davis GE, Cleaver O, Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signaling. Dev Cell. 2011 Apr 19;20(4):526-39
1J:87724 Yoshitomi H, Zaret KS, Endothelial cell interactions initiate dorsal pancreas development by selectively inducing the transcription factor Ptf1a. Development. 2004 Feb;131(4):807-17
1*J:178989 Yvernogeau L, Auda-Boucher G, Fontaine-Perus J, Limb bud colonization by somite-derived angioblasts is a crucial step for myoblast emigration. Development. 2012 Jan;139(2):277-87

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/21/2024
MGI 6.23
The Jackson Laboratory